- InChI
- InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
- InChI Key
- CGIGDMFJXJATDK-UHFFFAOYSA-N
- Formula
- C19H16ClNO4
- SMILES
-
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C
(=O)c1ccc(Cl)cc1 - Molecular Weight1
- 357.79
- CAS
- 53-86-1
- Other Names
-
- (1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-yl)acetic acid
- 1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-acetic acid (indomethacin)
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
- 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
- 1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indole-acetic acid
- 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
- 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid
- 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-acetic acid
- 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
- 1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico
- 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-
- 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
- Amuno
- Argun
- Artracin
- Artrinovo
- Artrivia
- Bonidin
- Catlep
- Chibro-amuno
- Chrono-indicid
- Confortid
- Dolcidium
- Dolovin
- Durametacin
- Elmetacin
- Idomethine
- Imbrilon
- Inacid
- Indacin
- Indo-Rectolmin
- Indo-phlogont
- Indo-tablinen
- Indocid
- Indocin
- Indocollyre
- Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-
- Indomecol
- Indomed
- Indomee
- Indometacin
- Indometacine
- Indometacyna
- Indomethacine
- Indomethazine
- Indomethine
- Indometicina
- Indomod
- Indonol
- Indoptic
- Indoptol
- Indorektal
- Indoxen
- Inflazon
- Infrocin
- Innamit
- Inteban
- Inteban sp
- Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy
- Lausit
- Metacen
- Metartril
- Methazine
- Metindol
- Mezolin
- Miametan
- Mikametan
- Mobilan
- N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid
- N-p-Chlorbenzoyl-5-methoxy-2-methylindole-3-acetic acid
- NCI-C56144
- Reumacide
- Rheumacin LA
- Sadoreum
- Tannex
- Vonum
- «alpha»-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid
- «alpha»-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid
- ΔfusH° : Enthalpy of fusion at standard conditions (kJ/mol).
- ΔfusH : Enthalpy of fusion at a given temperature (kJ/mol).
- log10WS : Log10 of Water solubility in mol/l.
- logPoct/wat : Octanol/Water partition coefficient.
- McVol : McGowan's characteristic volume (ml/mol).
- Inp : Non-polar retention indices.
- Tfus : Normal melting (fusion) point (K).
- 1: Molecular weight from the IUPAC atomic weights tables.
Cheméo is a service of Céondo GmbH, since 2007, we provide simulation, modelling and software development services for the industry.
Do not hesitate to contact us for your projects.
Physical Properties
| Property | Value | Unit | Source |
|---|---|---|---|
| ΔfusH° | 55.10 | kJ/mol | Thermod... |
| log10WS | [-4.69; -2.94] |
|
|
| log10WS | -4.69 | Aq. Sol... | |
| log10WS | -2.94 | Aq. Sol... | |
| logPoct/wat | 3.927 | Crippen Calculated Property | |
| McVol | 252.990 | ml/mol | McGowan Calculated Property |
| Inp | [2680.00; 2685.00] |
|
|
| Inp | 2680.00 | NIST | |
| Inp | 2685.00 | NIST | |
| Inp | 2680.00 | NIST | |
| Tfus | [432.10; 433.60] | K |
|
| Tfus | 432.10 | K | Aq. Sol... |
| Tfus | 432.10 | K | Aq. Sol... |
| Tfus | 433.60 | K | Solubil... |
| Tfus | 433.10 | K | (Solid ... |
| Tfus | 433.00 ± 1.00 | K | NIST |
Temperature Dependent Properties
| Property | Value | Unit | Temperature (K) | Source |
|---|---|---|---|---|
| ΔfusH | [36.49; 43.50] | kJ/mol | [433.00; 435.20] |
|
|
T(K) Enthalpy of fusion at a given temperature (kJ/mol) 36 38 40 42 44 433 434 435 | ||||
| ΔfusH | 37.90 | kJ/mol | 433.00 | NIST |
| ΔfusH | 37.80 | kJ/mol | 433.00 | NIST |
| ΔfusH | 39.99 | kJ/mol | 434.00 | NIST |
| ΔfusH | 43.50 | kJ/mol | 434.50 | NIST |
| ΔfusH | 36.50 | kJ/mol | 435.20 | NIST |
| ΔfusH | 36.49 | kJ/mol | 435.20 | NIST |
Similar Compounds
Find more compounds similar to Indomethacin.
Mixtures
- Indomethacin + Ethanol + Ethyl Acetate
- Indomethacin + Ethanol + Water
- Indomethacin + Water
- Indomethacin + Ethanol
- Indomethacin + 1-Octanol
- Indomethacin + Methyl Alcohol + Niacinamide
- Indomethacin + Methyl Alcohol
- Indomethacin + Ethyl Acetate + Methyl Alcohol
- Indomethacin + Ethyl Acetate
- n-Hexane + Indomethacin
- Indomethacin + Carbon Tetrachloride
- Indomethacin + Acetonitrile
- Indomethacin + Benzene, chloro-
- Trichloromethane + Indomethacin
- Indomethacin + Acetone
- Indomethacin + Pentane
- Indomethacin + Heptane
- Indomethacin + Cyclohexane
- Indomethacin + 1,2-Ethanediol
- Toluene + Indomethacin
Find more mixtures with Indomethacin.
Sources
- Crippen Method
- Solubility and preferential solvation of indomethacin in 1,4-dioxane + water solvent mixtures
- Thermodynamic analysis and enthalpy-entropy compensation for the solubility of indomethacin in aqueous and non-aqueous mixtures
- Solution thermodynamics of indomethacin in propylene glycol + water mixtures
- Solubility of pharmaceuticals in water and alcohols
- (Solid + liquid) phase diagram for (indomethacin + nicotinamide)- methanol or methanol/ethyl acetate mixture and solubility behavior of 1:1 (indomethacin + nicotinamide) co-crystal at T = (298.15 and 313.15) K
- Solubilities of Organic Semiconductors and Nonsteroidal Anti-inflammatory Drugs in Pure and Mixed Organic Solvents: Measurement and Modeling with Hansen Solubility Parameter
- Aqueous Solubility Prediction Method
- Aqueous Solubility Prediction Method
- McGowan Method
- NIST Webbook
Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more. Take the time to validate and double check the source of the data.