Chemical Properties of Betamethasone (CAS 378-44-9)

Betamethasone

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InChI
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m1/s1
InChI Key
UREBDLICKHMUKA-FGEXTOQASA-N
Formula
C22H29FO5
SMILES
CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO
Molecular Weight1
392.46
CAS
378-44-9
Other Names
  • (11«beta»,16«beta»)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • (11«beta»,16«beta»)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • 16-«beta»-Methyl-1,4-pregnadiene-9-«alpha»-fluoro-11-«beta»,17-«alpha»,21-triol-3,20-dione
  • 16-«beta»-Methyl-1,4-pregnadiene-9-«alpha»-fluoro-11-«beta»,17-«alpha»,21-triol-3,20-dione
  • 9-Fluoro-11«beta»,17,21-trihydroxy-16«beta»-methylpregna-1,4-diene-3,20-dione
  • 9-Fluoro-11«beta»,17,21-trihydroxy-16«beta»-methylpregna-1,4-diene-3,20-dione
  • 9-Fluoro-16«beta»-methylprednisolone
  • 9-Fluoro-16«beta»-methylprednisolone
  • 9-«alpha»-Fluoro-11-«beta»,17,21-trihydroxy-16-«beta»-methylpregna-1,4-diene-3,20-dione
  • 9-«alpha»-Fluoro-11-«beta»,17-«alpha»,21-trihydroxy-16-«beta»-methylpregna-1,4-diene-3,20-dione
  • 9-«alpha»-Fluoro-16-«beta»-methyl-1,4-pregnadiene-11-«beta»,17-«alpha»,21-triol-3,20-dione
  • 9-«alpha»-Fluoro-11-«beta»,17,21-trihydroxy-16-«beta»-methylpregna-1,4-diene-3,20-dione
  • 9-«alpha»-Fluoro-11-«beta»,17-«alpha»,21-trihydroxy-16-«beta»-methylpregna-1,4-diene-3,20-dione
  • 9-«alpha»-Fluoro-16-«beta»-methyl-1,4-pregnadiene-11-«beta»,17-«alpha»,21-triol-3,20-dione
  • 9«alpha»-Fluoro-16«beta»-methylprednisolone
  • 9«alpha»-Fluoro-16«beta»-methylprednisolone
  • Bebate
  • Becort
  • Bedifos
  • Betacorlan
  • Betacortril
  • Betadexamethasone
  • Betamamallet
  • Betametasone
  • Betamethazone
  • Betapredol
  • Betasolon
  • Betnelan
  • Betsolan
  • Celestene
  • Celestone
  • Cidoten
  • Corticosterone, 1-dehydro-9-fluoro-17-hydroxy-16«beta»-methyl-
  • Corticosterone, 1-dehydro-9-fluoro-17-hydroxy-16«beta»-methyl-
  • Dermabet
  • Desacort-beta
  • Desacort-«beta»
  • Desacort-«beta»
  • Flubenisolone
  • Hormezon
  • Methazon
  • NSC-39470
  • Prednisolone, 9-fluoro-16«beta»-methyl-
  • Prednisolone, 9-fluoro-16«beta»-methyl-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11«beta»,16«beta»)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11«beta»,16«beta»)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11«beta»,17,21-trihydroxy-16«beta»-methyl-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11«beta»,17,21-trihydroxy-16«beta»-methyl-
  • Pregna-1,4-diene-3,20-dione, 9alpha-fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-
  • Rinderon
  • Rinderon A
  • Sch 4831
  • Valisone
  • Visubeta
  • «beta»-Corlan
  • «beta»-Methasone
  • «beta»-Methasone alcohol
  • «beta»-Corlan
  • «beta»-Methasone
  • «beta»-Methasone alcohol
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Physical Properties

Property Value Unit Source
Δf -542.43 kJ/mol Joback Calculated Property
Δfgas -1056.40 kJ/mol Joback Calculated Property
Δfus 32.38 kJ/mol Joback Calculated Property
Δvap 120.70 kJ/mol Joback Calculated Property
log10WS -3.77 Aq. Sol...
logPoct/wat 1.896 Crippen Calculated Property
McVol 291.320 ml/mol McGowan Calculated Property
Pc 1973.55 kPa Joback Calculated Property
Tboil 1134.15 K Joback Calculated Property
Tc 1389.42 K Joback Calculated Property
Tfus 785.74 K Joback Calculated Property
Vc 1.103 m3/kmol Joback Calculated Property

Temperature Dependent Properties

Property Value Unit Temperature (K) Source
Cp,gas [1266.64; 1708.64] J/mol×K [1134.15; 1389.42] Show Hide
Cp,gas 1266.64 J/mol×K 1134.15 Joback Calculated Property
Cp,gas 1322.47 J/mol×K 1176.69 Joback Calculated Property
Cp,gas 1384.52 J/mol×K 1219.24 Joback Calculated Property
Cp,gas 1453.49 J/mol×K 1261.78 Joback Calculated Property
Cp,gas 1530.04 J/mol×K 1304.33 Joback Calculated Property
Cp,gas 1614.86 J/mol×K 1346.87 Joback Calculated Property
Cp,gas 1708.64 J/mol×K 1389.42 Joback Calculated Property

Similar Compounds

Dexamethasone. Fluoromethalone. 9Alpha-fluoro-16alpha-methylprednisolone-21-phosphate disodium salt. Triamcinolone. Betamethasone-17-valerate. Dexamethasone-21-acetate. Flumethasone. Betamethasone dipropionate. Triamcinolone diacetate. Dexamethasone tetra-TMS. Pregn-4-ene-3,20-dione, 9alpha-fluoro-11,17alpha,21-trihydroxy-, 21- acetate. 9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one. Triamcinolone Acetonide. 17-epi-Fluoxymesterone, 17-TMS. Triamcinolone tetra-TMS.

Find more compounds similar to Betamethasone.

Sources

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