Chemical Properties of Temazepam (CAS 846-50-4)

InChI

InChI=1S/C16H13ClN2O2/c1-19-13-8-7-11(17)9-12(13)14(18-15(20)16(19)21)10-5-3-2-4-6-10/h2-9,15,20H,1H3

InChI Key

SEQDDYPDSLOBDC-UHFFFAOYSA-N

Formula

C16H13ClN2O2

SMILES

CN1C(=O)C(O)N=C(c2ccccc2)c2cc(Cl)ccc21

Molecular Weight¹

300.74

CAS

846-50-4

Other Names

• 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-
• Crisonar
• ER 115
• K-3917
• Levanxene
• Levanxol
• Methyloxazepam
• N-Methyloxazepam
• Oxydiazepam
• Ro 5-5345
• Wy-3917
• 3-Hydroxydiazepam
• Euhypnos
• Hydroxydiazepam
• Mabertin
• Restoril
• Signopam
• 7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
• 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-3-hydroxy-1-methyl-5-phenyl-
• Cerepax
• 1,3-Dihydro-7-chloro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
• Normison
• Planum
• Remestan
• Euipnos
• Gelthix
• Levanzene
• Perdorm
• Ro-5-5354
• Diazepam, 3-hydroxy
• NSC 246303
• Tenox
• 7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one (temazepam)

• Δ_fusH : Enthalpy of fusion at a given temperature (kJ/mol).
• log₁₀WS : Log10 of Water solubility in mol/l.
• logP_oct/wat : Octanol/Water partition coefficient.
• McVol : McGowan's characteristic volume (ml/mol).
• I_np : Non-polar retention indices.
• ¹: Molecular weight from the IUPAC atomic weights tables.

Physical Properties

Property	Value	Unit	Source
log10WS	-3.39		Crippen Calculated Property
logPoct/wat	2.472		Crippen Calculated Property
McVol	213.260	ml/mol	McGowan Calculated Property
Inp	[2554.00; 2691.50]
Inp	2589.00		NIST
Inp	2613.00		NIST
Inp	2589.00		NIST
Inp	2588.00		NIST
Inp	Outlier 2691.50		NIST
Inp	2600.00		NIST
Inp	2554.00		NIST
Inp	2554.00		NIST
Inp	2575.00		NIST
Inp	2613.00		NIST
Inp	2590.00		NIST
Inp	2595.00		NIST
Inp	2595.00		NIST

Temperature Dependent Properties

Property	Value	Unit	Temperature (K)	Source
ΔfusH	[25.58; 27.40]	kJ/mol	[432.50; 432.60]
ΔfusH	25.58	kJ/mol	432.50	NIST
ΔfusH	27.40	kJ/mol	432.60	NIST

Similar Compounds

Find more compounds similar to Temazepam.

Sources

• Crippen Method
• Crippen Method
• McGowan Method
• NIST Webbook

Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more. Take the time to validate and double check the source of the data.
Outlier This icon means that the value is more than 2 standard deviations away from the property mean.