Chemical Properties of (-)-Norephedrine (CAS 492-41-1)

InChI

InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1

InChI Key

DLNKOYKMWOXYQA-VXNVDRBHSA-N

Formula

C9H13NO

SMILES

CC(N)C(O)c1ccccc1

Molecular Weight¹

151.21

CAS

492-41-1

Other Names

• Benzenemethanol, «alpha»-(1-aminoethyl)-, [R-(R*,S*)]-
• L-norephedrine
• Norephedrine, (-)-
• Benzyl alcohol,«alpha»-(1-aminoethyl)-
• Mydriatin
• USAF CS-6
• 1-Propanol, 2-amino-1-phenyl-, (-)-
• 2-Amino-1-phenyl-1-propanol
• (-)-Norephedrin
• (1R,2S)-(-)-Norephedrine
• Phenylpropanolamine
• (1R,2S)-2-Amino-1-phenyl-1-propanol
• (1R,2S)-Norephedrine
• (R,S)-(-)-Norephedrine
• Benzenemethanol, «alpha»-((1S)-1-aminoethyl)-, («alpha»R)-
• erythro-(1R,2S)-Norephedrine
• l-Phenylpropanolamine
• NSC 17704
• [R-(R*,S*)]-«alpha»-(1-aminoethyl)benzyl alcohol
• (-) 2-Amino-1-phenyl-1-propanol (norephedrine)

• C_p,gas : Ideal gas heat capacity (J/mol×K).
• Δ_fG° : Standard Gibbs free energy of formation (kJ/mol).
• Δ_fH°_gas : Enthalpy of formation at standard conditions (kJ/mol).
• Δ_fusH° : Enthalpy of fusion at standard conditions (kJ/mol).
• Δ_fusH : Enthalpy of fusion at a given temperature (kJ/mol).
• Δ_vapH° : Enthalpy of vaporization at standard conditions (kJ/mol).
• log₁₀WS : Log10 of Water solubility in mol/l.
• logP_oct/wat : Octanol/Water partition coefficient.
• McVol : McGowan's characteristic volume (ml/mol).
• P_c : Critical Pressure (kPa).
• I_np : Non-polar retention indices.
• I : Polar retention indices.
• T_boil : Normal Boiling Point Temperature (K).
• T_c : Critical Temperature (K).
• T_fus : Normal melting (fusion) point (K).
• V_c : Critical Volume (m³/kmol).
• ¹: Molecular weight from the IUPAC atomic weights tables.

Physical Properties

Property	Value	Unit	Source
ΔfG°	62.06	kJ/mol	Joback Calculated Property
ΔfH°gas	-121.56	kJ/mol	Joback Calculated Property
ΔfusH°	15.35	kJ/mol	Joback Calculated Property
ΔvapH°	64.45	kJ/mol	Joback Calculated Property
log10WS	-1.96		Crippen Calculated Property
logPoct/wat	1.067		Crippen Calculated Property
McVol	129.760	ml/mol	McGowan Calculated Property
Pc	3975.52	kPa	Joback Calculated Property
Inp	[1287.00; 1339.00]
Inp	1291.00		NIST
Inp	1310.00		NIST
Inp	1310.00		NIST
Inp	1313.00		NIST
Inp	1308.00		NIST
Inp	1308.00		NIST
Inp	1287.00		NIST
Inp	1300.00		NIST
Inp	1304.00		NIST
Inp	1321.00		NIST
Inp	1331.00		NIST
Inp	1331.00		NIST
Inp	1332.00		NIST
Inp	Outlier 1339.00		NIST
Inp	1289.00		NIST
Inp	1287.00		NIST
Inp	1308.00		NIST
Inp	1304.00		NIST
Inp	1310.00		NIST
Inp	1313.00		NIST
Inp	1326.00		NIST
Inp	1310.00		NIST
Inp	1304.00		NIST
I	2231.00		NIST
Tboil	595.83	K	Joback Calculated Property
Tc	808.08	K	Joback Calculated Property
Tfus	331.69	K	Joback Calculated Property
Vc	0.468	m3/kmol	Joback Calculated Property

Temperature Dependent Properties

Property	Value	Unit	Temperature (K)	Source
Cp,gas	[323.04; 384.09]	J/mol×K	[595.83; 808.08]
Cp,gas	323.04	J/mol×K	595.83	Joback Calculated Property
Cp,gas	335.03	J/mol×K	631.21	Joback Calculated Property
Cp,gas	346.24	J/mol×K	666.58	Joback Calculated Property
Cp,gas	356.72	J/mol×K	701.96	Joback Calculated Property
Cp,gas	366.49	J/mol×K	737.33	Joback Calculated Property
Cp,gas	375.60	J/mol×K	772.71	Joback Calculated Property
Cp,gas	384.09	J/mol×K	808.08	Joback Calculated Property
ΔfusH	15.87	kJ/mol	324.40	NIST

Similar Compounds

Find more compounds similar to (-)-Norephedrine.

Sources

• Crippen Method
• Crippen Method
• Joback Method
• McGowan Method
• NIST Webbook

Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more. Take the time to validate and double check the source of the data.
Outlier This icon means that the value is more than 2 standard deviations away from the property mean.